Kazushige Yokoyama

Professor of Chemistry
ISC 326F
(585) 245-5320
yokoyama@geneseo.edu
he/him

Dr. Yokoyama has been a member of the Geneseo faculty since 2001.

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Kazu Yokoyama

Fall 2024 Office Hours

Mon 2:00p-4:00p
Tues 2:00p-4:00p
Thurs 2:00p-4:00p
Fri 2:00p-4:00p
or by appointment

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Curriculum Vitae

Education

  • B.S. & M.S. University of Kobe, Japan (with Professor Hajime Kato)

  • Ph.D. University of Colorado (with Professor Carl Lineberger)

  • Post-Doctoral Fellow at University of Minnesota (with Professor Paul Barbara)

Publications: Papers

  • K. Yokoyama, E. Barbour, R. Hirschkind, Bryan Martinez Hernandez, K. Hausrath, and Theresa Lam
    鈥淧rotein Corona Formation and Aggregation Process of Amyloid beta 1-40 Coated Gold Nano-Colloids鈥, Langmuir, Vol. 40, pp. 1728-1746 (2024).

    K. Yokoyama, J. Thomas, W. Ardner, M. Kieft, L. Neuwirth, and W. Lieu, 鈥淎n Approach for In Situ Detection of Amyloid Formations within the Hippocampus of the Cohen鈥檚 Alzheimer鈥檚 Disease Rat Model by Surface Enhanced Raman Scattering Methods鈥, Journal of Neuroscience Methods, Vol. 393 pp. 109892 - 109901 (2023)

    K. Yokoyama and A. Ichiki, 鈥淎dsorption of Amyloidogenic Peptides at Nano-Scale Interface Studied by Spectroscopic Approach鈥, Journal of Visualized Experiments (under the review).

    K. Yokoyama, T. Lam, J. Santariello, and A. Ichiki, 鈥淣ano-size dependent Reversible Self-assembly of SARS-CoV-2 Omicron Spike protein鈥, Colloids and Surfaces A, Volume 647 128967 - 128973 (2022)

    K. Yokoyama and A. Ichiki, 鈥淎 Model for Nano-Scale Spherical Surface Coverage and Protein Corona Formation by Amyloidogenic Peptides , The International Journal of Biocomputing and Nano Technology Volume 1, pp. 21 鈥 28 (2022)

    K. Yokoyama and A. Ichiki
    "Nano-size Dependence in the Adsorption by the SARS-CoV-2 Spike Protein over Gold Colloid"
    [Colloid and Surfaces A,Volume 615, pp. 126275-126281 (2021)

    K. Yokoyama and A. Ichiki, "Nano-Size Dependence in the Adsorption by the SARS-CoV-2 Spike Protein over Gold Colloid", Colloids and Surfaces A, Vol. 40 pp. 100356-100362 (2021)

    K. Yokoyama and A. Ichiki, 鈥淲hat can peptide-coated nanoparticles tell us about the causes of dementia?鈥, Research OutreachJournal of Visualized Experiments, pp. 110-113, Issue 116 (2020)

    K. Yokoyama, K. Brown, P. Shevlin, J. Jenkins, E. D'Ambrosio, N. Ralbovsky, J. Battaglia, I. Deshmukh, and A. Ichiki, 鈥淓xamination of Adsorption Orientation of Amyloidogenic Peptides Over Nano-Gold Colloidal Particles鈥 Surfaces鈥, Int. J. Mol. Sci., Vol 20, pp. 5354-5380 (2019).

    K. Yokoyama, H. Chen, A. Islam, I. Deshmukh, P. Shevlin, K. Brown, and A. Ichiki, "Dynamical Investigation of Adsorption Orientation of Amyloid Beta Peptide 1-40 at Nano-Scale Gold Surface鈥, BAOJ Chemistry, Vol. 5 (1), pp. 1-20 (2019).

Publications: Text Book & Book Chapters

  • [TEXT BOOKS]
    K. Yokoyama 鈥淢odern Physical Chemistry for Bioscience Students - Friendly and Short Cut Guide for Physical Chemistry鈥 (2011) Linus Publication, ISBN# 1-60797-185-2 First Edition (604 pages), ISBN# 1-60797-246-8 Second Edition.(618 pages), ISBN# 1-60797-337-5 Third Edition.(592  pages), ISBN978-1-60797-897-8 (2020)

    K. Yokoyama (Editor) 鈥淔rontiers in Nanoscience for Biomedical Research鈥  Research Signpost, ISBN# 978-81-308-0537-5, (2014).

  • [Book Chapters]
    K. Yokoyama, 鈥淚nvestigation of protein-protein interaction utilizing nano-gold colloid surface plasmon resonance: Application to SARS CoV-2 spike protein coated gold colloids鈥, ACS Symposium Series Volume 1428, Physical Chemistry Research at Undergraduate Institutions 鈥 Innovative and impactful approaches Volume 2, Chapter 9 pp. 145-164, (2023) Edited by Todd Hopkins and Carol Parish, ISBN 978-0-8412-9743-2.

    Kazushige Yokoyama, Kieran Brown, Peter Shevlin, Jack Jenkins, Elizabeth D鈥橝mbrosio, Nicole Ralbovsky, Jessica Battaglia, Ishan Deshmukh and Akane Ichiki, "Examination of Adsorption Orientation of Amyloidogenic Peptides Over Nano-Gold Colloidal Particle Surfaces" pp. 75-102 in " Designer Biopolymers Self-Assembling Proteins and Nucleic Acids " Edited by Ayae Sugawara-Narutaki Yukiko Kamiya MDPI, Basel, Switzerland (2020)
    ISBN 978-3-03936-370-4

  • K. Yokoyama and A. Ichiki "Chapter 3: Oligomerization and Adsorption Orientation of Amyloidogenic Peptides over Nano-Gold Colloidal Particle Surfaces鈥 pp. 139-194 in Advances in Chemical Research, Ed. by James C. Taylor, Nova Science Publishing, Hauppauge, NY, USA. (2020) ISBN: 978-1-53617-627-8.

  • K. Yokoyama, K. Brown, P. Shevlin, J. Jenkins, E. D鈥橝mbrosio, N. Ralbovsky, J. Battaglia, I. Deshmukh and Akane Ichiki, 鈥淓xamination of Adsorption Orientation of Amyloidogenic Peptides Over Nano-Gold Colloidal Particle Surfaces鈥, e-Book Book Chapter, Prime Archives in Molecular Biology, VideLeaf.

  • Kazushige Yokoyama 鈥淐ontrolling Reversible Self Assembly Path of Amyloid Beta Peptide over Gold Colloidal nanoparticle鈥檚 Surface鈥 Book Chapter in 鈥淣anoscale Spectroscopy with Applications鈥 Sarhan M. Musa 鈥揈d (CRC Press-Taylor and Francis Group, LLC) ISBN# 9781466568532 (2013) []

  • Kazushige Yokoyama 鈥淣ano Size Dependent Properties of Colloidal Surfaces鈥 Book Chapter in 鈥淐olloids: Classification, Properties and Applications鈥 (Nova Science Publishing) (2012)

Media Related

  • ACS Chemical Engineering News 鈥 Pictures in Chemistry (November, 2022)
    White light image of Amyloid beta 12-28 coated Gold colloid aggregates
    ()

  • Science Animation
    YouTube "How do fibrils form?"

  • Yokovid Project "Geneseo Community Outreach through Science of COVID-19"
    YouTube

  • Pod-Cast "Dimentia, degeneration, and gold nanoparticles"

  • Research Outreach (Science Magazine)
    Kazushige Yokoyama & Akane Ichiki
    "What can peptide-coated nanoparticles tell us about the causes of dementia?"
    Issue 116 (pp. 110-113)

  • COVID Information Commons (CIC) Webinar: Winter 2024 Research Lightning Talks and Q & A

    K. Yokoyama 鈥滻nvestigating Reversible Aggregation of SARS-CoV-2 Spike Protein-Coated Gold Colloid鈥

Research Group Members

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From the left:
Christopher Kolilias ('26, Chemistry), Victoria Brzezinski ('25, Biology), Nathan Bobowski ('28, Chemistry), Mitsuki Tabei ('26, Biophysics), , Nicole Mathewson ('26, Biology).

黑料网 COVID19 Study Group (Team Yokovid)

Journal Editorial Role

Guest Editor: MDPI-"Surfaces" Special Issue  

Editorial Board Member of

Textbooks/Media

K. Yokoyama (Editor) 鈥淔rontiers in Nanoscience for Biomedical Research鈥  Research Signpost, ISBN# 978-81-308-0537-5, (2014)

Frontiers in Nanoscience for Biomedical Research

K. Yokoyama
Friendly and Short Cut Guide for Physical Chemistry
Modern Physical Chemistry for Bioscience Students
(4th edition) Linus Learning  ISBN978-1-60797-897-8 (2020) 
[]
Physical Chemistry by Yokoyama

Problemset 
Modern Physical Chemistry for Bioscience Students
Linus Learning (2021) ISBN 978-1-60797-931-9 

Media (YouTube/iPod)

  • Science behind COVID-19 (Community Outreach Project)
    Brochure & You Tube
  • Podcast: ResearchPod 鈥淒ementia, degeneration, and gold nanoparticles鈥 (2019)
  • Video Abstract 鈥淣anoparticles and dementia: understanding the role of fibrils鈥 (2019)
  • Research Outreach 鈥淲hat can peptide-coated nanoparticles tell us about?鈥 Issue No. 116, pp. 110-113 (2020). (Research Outreach Featured Article page: )
  • Science Animation 鈥淗ow do fibrils form?鈥 (2020)
  • Yokoyama, K., Thomas, J., Ardner, W., Neuwirth, L.S. & Liu, W. Method for in situ detection of amyloid formation in the hippocampus of the Cohen's Alzheimer's disease rat model by Surface Enhanced Raman Scattering. in SSRN (, 2022).

Classes

  • CHEM 104: Chemistry & Society

    A terminal one-semester course designed to acquaint non-science students with how chemistry and science affect their lives. Chemical principles are applied to problems of current interest, such as energy and pollution. Methods which chemists and other scientists use in their attempts to solve such problems are illustrated.

  • CHEM 105: Chemistry and Society Lab

    A terminal one-semester laboratory designed to acquaint non-science students with how chemistry and science affect their lives. Experiments are applied to problems of current interest, such as acid rain. Methods which chemists and other scientists use in their attempts to solve such problems are introduced.

  • CHEM 118: Chemistry II

    A continuation of CHEM 116. Topics to be covered include thermodynamics and reaction spontaneity, chemical kinetics, chemical equilibrium, properties of acids and bases, aqueous solution equilibria, electrochemistry, molecular structure and bonding theories, transition metals and their coordination compounds, and chemical properties of selected elements.

  • CHEM 129: Intro to Lab Research in Chem

    An introduction to research methods used in chemistry laboratories. Topics include utilizing chemical literature, experimental design and iteration, and scientific communication. Students complete a quantitative analysis project utilizing spectroscopic methods and write a technical report describing their work.